Kre-Alkalyn is the newest form of Creatine. It was patented in 2008. The author of the patent for Kre-Alkalyn is the same person who discovered Arginine Alpha Keto Gluturate (AAKG) converted to Nitic Oxide in the muscles, and how NO benefited weight lifters.
In his research he found that Creatine Monohydrate broke down extremely quickly in high pH environments to Creatinine, and because of the acidic environment of the human stomach, Creatine Monohydrate was only half, or less, effective as it could be if it was more stable.
Kre-Alkalyn is just Creatine Monohydrate that has a pH buffer. What this scientifically means, is that during the manufacturing process, the Creatine on the molecular level, artificially has its pH levels raised by adding a positively charged ion to the compound. Therefore producing an "acid" like quality. Because the Creatine has this positive pH level, your stomach acids are repelled and don't interact with the Creatine to break it down into Creatinine. (Think two positively charged magnates)
A great benefit of having the Creatine staying in its pure form, is that it then doesn't have any fillers attached to it which may block the absorption of it into the muscles. This form delivers the purest form of Creatine to the muscle cells, therefore giving the best performance.
The exciting part, is that because it absorbs at the correct rate, while attracting the correct amount of sodium into the muscles, which in turn add to the available energy for the muscle fiber, there isn't as much water absorbed into muscle fibers as other forms, which allows more water to be readily available for other cells, and reducing the "bloat" to next to zero.
This has a lesser effect of having a less volumizing effect while on Kre-Alkalyn, but also more gains are retained after a cycle, because less water is flushed from the muscle fibers.
All of these factors point to Kre-Alkalyn being the best performing Creatine on the market, with the least opportunity for negative side effects from use.
Because Kre-Alkalyn does not break down into Creatinine very easily, and is easily absorbed into the muscle fibers, regular dosages are 3G~6G per day.
Although Kre-Alkalyn has been shown to generally work for most individuals, those with lower pH levels of stomach acid, have been shown to have a lower rate of return from Kre-Alkalyn because the acids in their stomachs are more likely to interact with the buffered Creatine, causing it to break down more into Creatinine. Unfortunately it's extremely hard to test for pH levels of stomach acids, so the only way to know what you have is to try out the different forms and see which ones work best.
Tags: creatine ethyl ester, creatine kre-alkalyn, creatine monohydrate