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CDP Choline

Also known as: Citicholine Sodium, Citicoline, Cognizin

Many individuals turn to choline supplements to improve mental focus and cognitions. However, it's not easily taken up by the body. CDP-choline solves this problem and will give you unparalleled concentration leading you to have "tunnel vision."

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What is CDP-Choline?

Chemically known as cytidine-5-diphosphocholine, CDP-choline is a naturally occurring molecule in the body. Also known as citicoline, it exists as an intermediate in the production of phosphatidylcholine (a phospholipid that makes up cell membranes). CDP-choline is a nucleotide composed of choline, cytosine, pyrophosphate, and ribose.

Although most people supplement with choline to increase acetylcholine levels in the brain, CDP-choline increases levels in the brain more effectively than more traditional forms. CDP-choline is also a nootropic compound that converts to choline and cytidine in the body and has been shown to improve cognition and focus.

Where Does It Come From?

CDP-choline is generated in the body from choline during the synthesis of phosphatidylcholine. Cell membranes are composed of various phospholipids, and phosphatidylcholine is the most common component of these membranes.

CDP-choline doesnt exist on its own if food sources, but its predecessor, choline does. Choline is found in many protein and fat containing foods, such as eggs, meat, chicken, cauliflower, peanuts and soybeans. Another option though is to purchase a CDP-choline supplement which would be a more direct route to increase citicoline levels in the body.

What does it do?

Our brains require choline to function properly. It is a precursor to the neurotransmitter acetylcholine which is one of the many neurotransmitters responsible for conducting signals in the central nervous system (CNS). One of its most important functions is in maintaining focus and attention. Individuals with low acetylcholine levels or that have suffered brain damage have been shown to experience gaps in memory and Alzheimers disease. Additionally, a lack of acetylcholine is a leading cause of depression.

In order to produce acetylcholine, your body needs a steady supply of choline. This neurotransmitter acts on the peripheral nervous system and central nervous system.

Choline has also been shown to improve the intra-cellular communication between brain cells. Additionally, citicoline increases blood flow and energy production in brain while reducing inflammation and protecting the blood-brain barrier.

CDP-Choline also has a history of use in the medical field for treating a number of mental injuries, diseases and illnesses. Benefits from CDP-choline supplementation have been observed in the treatment of Alzheimers, Parkinsons, traumatic brain injury (stroke), hypoxia, and cerebral ischemia. Aside from increasing production of acetylcholine, it boosts production of dopamine, serotonin and norepinephrine, leading to that feel-good feeling many describe.

In the context of pre workouts, CDP-choline is often included to improve focus and mental energy. This naturally allows you to train better as youll be more focused and engaged in your workout, helping to foster a better mind-muscle connection. Youll also be less likely to get distracted during your workouts often experiencing tunnel vision.

Benefits of CDP-Choline

  • Improve focus and mental energy

  • Enhance learning capability

  • Prevent memory impairment

  • Help treat ADD and ADHD

  • Improve memory retention

  • Promotes brain metabolism

  • Better mind-muscle connection

  • Improved mood and sense of well-being


Several studies on CDP-choline have shown beneficial effects with doses ranging from 500mg to 2,000mg. Some experience adverse reactions when using high doses of CDP-choline. For this reason, its suggested to start at the lower dose and then gradually work your way up depending on how you respond.


CDP-choline is an excellent supplement for anyone looking to improve their focus and support optimal brain functioning. Whether youre studying for finals or grinding out set after set in the gym, CDP-choline can give you the mental boost you need to stay on task and make the most of your time spent studying or lifting. Dont settle for less effective choline supplements, invest in this more bioavailable form and be ready for unparalleled focus and concentration.

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