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Slintensity™ Reviews

By: EvoMuse



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Growth Enhancers > Nutrient Repartitioners
ABOUT
Slintensity™ is a Nutrient Repartitioner manufactured by EvoMuse. It is meant to help the body use the macronutrients of protein, carbohydrates and fats more efficiently.
PRODUCT RATING
7.7
(Out of 10, after 3 reviews)
3

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REVIEWS (3)



Overall
Overall
8.5
Effectiveness
Effectiveness
9.0
Value
Value
8.5
Full-Container Received through SR TROOPs.
Thanks to EvoMuse for sending it out!
(Show run details )
  October 28, 2017

 Pros:
 Cons:
  • Good Value
  • Open Label
  • Muscle Fullness
  • Consistent Pump
  • Hard To Evaluate The Dosages

Introduction

What up SR!! A big thank you to Evomuse for sending this out and participating in the trooper program & of course SR for making this all possible!

This was my first go around with a nutrient repartitioner, but i know how my body responds to high amounts of carbohydrates; for this reason, my lack of experience shouldn't cause any hindrances.

Edit: I have since used ASSASSINATE from Olympus Labs and can compare the two

On to the review!

Ingredient Profile

As stated by recent members reviewing this product.. NutraPlanet lists each ingredient, its intended effects, & different diets that the product works in conjunction with here: https://nutraplanet.com/products/evomuse-slintensity-60-cap/... If you are too busy reading to copy and paste in the new tab however, heres the write up from NutraPlanet on the ingredient aspect:

"Let's take a look at each of the ingredients and how they work.
Banaba blend (Corosolic Acid/mixed elaggitannins)
Coming from the banaba leaf, this extract is standardized for a high concentration of corosolic acid and mixed elaggitannins. The first published study dates all the way back to 1940, and is commonly used in folk medicine for diabetes.

Banaba has several powerful effects, the most important ones for our purposes relate to its interaction with blood sugar. It has been shown in numerous studies to decrease serum blood sugar after carbohydrate ingestion by enhancing glucose uptake at the muscle cell (1-8).

Banaba appears to carry out its effects through favorable signaling modulation of PPARa, PPARy, MAPK, and NF-kb, while significantly increasing insulin sensitivity and translocation of GLUT4 receptors to the outside of the cell membrane, giving insulin more places to dock and let the glucose in (1-3,7,9,10). It also appears to be an insulin mimetic, albeit acting in a different way than insulin itself (11).

Multiple studies have also elucidated banaba's ability to either decrease or inhibit gluconeogenesis, which is the basically the conversion of protein into glucose (1,2,12). This means less protein being wasted, and more available for muscle building.

Good news for blood lipids and other general health markers as well, take a look at these benefits:

Antihyperlipidemic (reduces elevated blood lipids) (1,2)
Reduces serum Triglycerides, FFA's, and hepatic lipid content (1,2,7,10,13,14)
Decreases blood pressure, oxidative stress, and inflammatory markers like CRP-hs (13)
Reduces HbA1c (which is typically thought of as a window into your last three months of blood sugar levels, however it is also an indicator of the level of Advanced Glycation End Products {AGE's} in the body) (7).
Increases adiponectin (10).

One group of researchers took genetically obese mice and fed them a fattening diet, and found that the addition of corosolic acid reduced fat gain by 15% over controls (10). And remember, this is in an obese model, where everything related to a functional metabolism is a disaster.

Finally, one last cool thing about banaba; it has been shown to suppress adipocyte differentiation, preventing stem cells from becoming mature fat cells (15).
4OH-Ile (4-hydroxyisoleucine)
4OH-Ile is an atypical branched-chain amino acid derived from fenugreek. Unlike banaba which has insulin like effects without stimulating extra insulin production, 4OH-Ile appears to directly stimulate glucose-induced insulin release from the pancreas. This effect is seen when blood glucose starts to rise above about 118mg/dL, which would be well above a fasting glucose for a healthy person but a pretty easily achieved post-prandial level for even a moderate carbohydrate meal. Also, the more blood glucose rises, the more insulin 4OH-Ile triggers, in a biphasic fashion (16).
Similar to banaba, 4OH-Ile has been shown to increase insulin sensitivity and glucose uptake in muscle cells, doing so by triggering translocation of GLUT4 receptors through the PI3-kinase/AKT pathway (17-21). However, even though 4OH-Ile stimulates insulin production in response to elevated blood sugar (i.e., carb intake), it also tends to lower fasting insulin levels (17,21).

Once cells become insulin resistant, a cascade of bad things starts to happen in the body. 4OH-Ile has demonstrated the ability to reverse many of these problems. Namely, reducing total cholesterol, LDL, triglycerides, TNFa, liver enzymes AST and ALT, and HbA1c, while elevating HDL (15,18,19,21,22).

So basically 4OH-Ile is going to crank up insulin production when it's beneficial to get more glucose and amino acids into the muscle cells, support normal levels while fasting, and help optimize blood lipids and inflammatory cytokines.
Momordin
Momordin is a titerpenoid saponin extracted from the bitter melon fruit. It is the third ingredient in the Slintensity formula shown to increase GLUT4 translocation in skeletal muscle cells, thereby encouraging better insulin sensitivity and higher glucose uptake (23). Momordin works, at least in part, through PI3K/MAPK dependent PPAR signaling (24,25). It has also been shown to increase AMPK phosphorylation and reduce the expression of PEPCK. One study looking at overfed mice showed that the addition of momordin caused less visceral fat gain and reduced glucose levels, triglycerides and fatty acid synthase (FAS) (26).

Momordin has also been shown to have a three-pronged attack on preventing fat gain in human fat cells by inhibiting its storage, increasing lipolysis, and inhibiting adipocyte differentiation (27). Finally, it also appears to slow gastric emptying which improves glucose metabolism and insulin signaling (28).
FMOC-L-Leu
FMOC-L-Leu is a derivative of the Amino Acid Leucine, with some highly unique effects. It acts as a ligand for PPARy, binding in a particular way that causes it to only activate the beneficial signaling pathways that we want. Specifically, it potently increases insulin sensitivity without increasing adipogenesis (often when insulin sensitivity is increased, it happens at both muscle and fat cells encouraging heightened uptake at both places, which is not ideal in a non-pathological state) (29).
Phellodendri Cortex 20:1
Extracted from the bark of the Phellodendron tree, Phellodendri Cortex contains two major compounds relevant to Slintensity, obacunone and berberine (30).

Obacunone does several beneficial things, let's take a look.

Arginase Inhibition
Nitric Oxide Synthase (NOS) competes with arginase for available L-arginine. Too much arginase, and the L-arginine substrate pool becomes depleted, leaving little left over for NOS to produce NO with. More NO allows us to take advantage of post meal vasodilation, encouraging enhanced delivery of nutrients to the cells. Obacunone has been demonstrated to be an arginase inhibitor, and subsequently boost NO production. It was even able to attenuate the effect of a vasoconstrictor (31).

TRG5 agonism
This is a protein that serves as a cell surface bile acid receptor. The activation of this receptor triggers intracellular cAMP production and MAPk signaling, demonstrating involvement in energy homeostasis. Interestingly, when this receptor is agonized it activates enzymes that convert the minimally active thyroid hormone T4 into the potent hormone T3. The ineffective conversion of T4 to T3 is quite common in people with suboptimal thyroid function, which can throw a wrench into fat loss and muscle gain, among other things.

TRG5 agonism, which obacunone has demonstrated capability for, has been shown to prevent elevated blood sugar and obesity in mice overfed a high fat diet (32,33).

P-gp (P-glycoprotein) inhibition
This glycoprotein carries several things through intra and extra-cellular membranes, and it can reduce the bioavailability of many pharmaceuticals and supplements. The intestinal barrier cells use P-gp to resist absorption of berberine, which likely accounts for reports of GI distress when users consume high doses of the compound. Obacunone has demonstrated significant P-gp inhibition capabilities, allowing for better bioavailability of berberine and other ingredients (30).

In addition to the above, obacunone also acts as an anti-aromatase, reduces inflammatory markers like NF-kB & COX2, activates the p38/MAPK pathway, and prevents glutamate induced neurotoxicity (34,35).

As for Berberine, a ton of research has been done on this compound assessing its beneficial effect on blood sugar, insulin and diabetes management, so we will avoid going through all of that for the sake of brevity and just look at a few interesting points.

In a recent randomized double blind placebo study, 24 subjects with metabolic syndrome participated; half were given berberine three times per day before meals. Those that received berberine compared to controls, saw reduced blood pressure, triglycerides, reduced AUC for glucose and insulin, increased insulin sensitivity, and an improvement in the Matsuda index (an index looking at the response to an oral glucose tolerance test) (36).

Berberine has also been shown to donwregulate lipogenetic genes and upregulate energy expenditure genes in adipose and muscle cells (37). It also appears to increase insulin sensitivity in a novel way, by having a somewhat dichotomous effect on mitochondria. It activates AMPK, then inhibits mitochondrial function, then when the berberine clears the extra AMPK enhances mitochondrial function, and the end result is enhanced glucose and FFA oxidation with improved insulin sensitivity (38).

Berberine also inhibits preadipocyte differentiation, and encourages the gut microbiota to shift towards the type that produce the extremely beneficial Short Chain Fatty Acids (SCFA's) (39,40).
Green Curry Leaf Extract
GCLE is exactly what it sounds like, also known as Murraya Koenigii. GCLE has been shown in numerous studies to have a glucose lowering effect, fasting and in response to a meal. It appears to do so by the familiar mechanism of increasing GLUT4 translocation causing enhanced glucose uptake at the muscle cell, as well as being another ingredient that actually stimulates insulin synthesis and secretion (41-46).

In addition, GLCE has also been shown to lower total cholesterol, triglycerides, reduce oxidative stress and pancreatic cell damage, inhibit glycation, and boost glutathione (41,43,46-49)."

Taste/Mixability/Dosing

This is in pill form, so the category isn't really relevent. Dosing however is very simple.. take one capsule per 60grams of carbs you plan to ingest (20-30min before eating).

Effectiveness

This is truly a product that shines during bulk season and that is apparent after the first few doses. I did use this during the summer and found that even with ketogenic carb cycling (which constantly confuses your body), slintensity helps provides the needed insulin response to stock the liver and muscles with absorbed glycogen; rather than allowing for storage of fat.

I saved a few doses of slintensity for bulk season and the results were even better... I don't know if I've ever had such consistent pumps as I did with this product. Slintensity shuttled all the glycogen my muscles could possibly hold, and provided me with better recovery by doing so.

Sure enough once usage is somewhat consistent, fat storage is pretty well a thing of the past; not only will tone seem to be better within muscle fibers, but muscle fullness is present the whole duration of supplementation. Just give it 1-2 weeks of consistent use.

Value

The value of Slintensity is right on, usually its about $25 for a brand new bottle. Today however, Slintensity isn't too widely available as everywhere i've looked.. is sold out

Side Effects

None to be noted.

Conclusion

Simply put, Slintensity is a great addition to anyones cycle if they look to optimize nutrient delivery, storage, and recovery in one simple product. I firmly believe Evomuse hit the nail on the head with this product, but as always, there is room for improvement! If you can get your hands on a bottle try it for yourself, you won't regret it!!



Overall
Overall
7.5
Effectiveness
Effectiveness
7.5
Value
Value
8.0
Full-Container Received through SR TROOPs.
Thanks to EvoMuse for sending it out!
(Show run details )
  July 21, 2017

 Pros:
 Cons:
  • Good Value
  • Open Label
  • Standardized Extracts
  • Hard To Evaluate The Dosages

Introduction

Before I start I want to thank EvoMuse for giving me the opportunity to review two of their supplements. I decided to try a stack of Slintensity and BRITE as part of a lean build. Before using these two supplements I have used a couple EvoMuse products in the past but its been a long long time. Since my daily schedule has drastically changed since having my first child, my workouts are a bit different. In the morning I get 30 min or so to do fasted cardio and another hour or 1:30 in the evening to weight train. My diet while using this stack was high protein/fat and lower carbs depending on the day.

Claim: Designed to help drive more nutrients into the muscle cells and away from fat, the idea behind SlinTensity is to make every meal more anabolic.

Ingredient Profile

The ingredient profile is a mixture of 6 different ingredients with many you may have never heard of. I could go on and on about the ingredients and fill up this review with 500 more words. However NutraPlanet actually goes in depth about each ingredient and giving you the differences this product gives you when your on a specific kind of diet. Check it out here: https://nutraplanet.com/products/evomuse-slintensity-60-cap/

Taste/Mixability/Dosing

Taste - There really isn't a taste to judge since these are in capsule form.

Mixability - No mixability to judge on either..... however the capsules are really easy to swallow.

Dosing - Slintensity works well even if your on a low or high carb diet. During this review I was on a low carb diet, usually having most of my carbs before my second workout in the evening. I took a single capsule 20-30 minutes before your targeted meal (dinner). A second capsule can be added if the carbohydrate content of the meal exceeds 60g (usually the case for that meal).

Effectiveness

In terms of effectiveness I noticed a few different things.....
-Leaner body composition
-Had more energy throughout the day
-Better bathroom trips ( no need to explain unless you really want to know)
-Felt better mentally

As I said in the introduction I was using Slintensity as part of an EvoMuse stack with BRITE. It took about two weeks for me to feel and notice any kind of results. I started noticing a leaner body composition especially around my mid-section losing 6lbs in total after 30 days. In the effectiveness column I said I felt better mentally which was very true. I didn't feel bad after a high carb session or having a cheat meal once a week. Because of this thought I had a better mood throughout the day and with carbs a burnin I had extra energy which is nice when you watch a new born through out the day.

Value

The cheapest value I could find was for around $25 on a variety of different online retailers. Each bottle contains 60 capsules (.42 cents per capsule) - the value really depends on how you use Slintensity. I used 2 capsules a day (.84 cents) which lasted me 30 days. For other users SlinTensity may last as long as 60 days. When compared to other nutrient partitioners the price seems to be in the same boat.

Side Effects

None

Conclusion

In conclusion I thought SlinTensity was a "good" nutrient partitioner. f your diet is one point and you have a sound training program then you'll notice good things from this supplement. For the price I'd recommend giving SlinTensity a try if your looking to lean out or feel better about your diet situation. Thanks again to EvoMuse!



Overall
Overall
7.7
Effectiveness
Effectiveness
7.5
Value
Value
8.0
Full-Container Received through SR TROOPs.
Thanks to EvoMuse for sending it out!
(Show run details )
  July 17, 2017

 Pros:
 Cons:
  • Open Label
  • Standardized Extracts
  • Good Value
  • Unclear What All Of The Ingredients Are
  • Hard To Evaluate The Dosages

Introduction

I'm a competing powerlifter currently coming back from a back injury. I'm doing a 6 day upper/lower split and am leaning down until it's time to get ready for my next competition. Basic Stack: protein powder, creatine, fish oil, pre-workout, and curcumin.

Ingredient Profile

Here, we have an open label glucose disposal agent from Evomuse. A GDA is a supplement used to reduce your blood glucose levels and make you more sensitive to insulin. They are often taken around high carb meals.

There are a number of ingredients in Slintensity that have been found to reduce blood glucose levels, improve insulin sensitivity, reduce LDL cholesterol, and increase HDL cholesterol.
It's hard to evaluate the doses of the ingredients in this product because Evomuse used standardized extracts instead of using whole herbs, and I could only find dosing information on the whole herbs. I included those doses for reference.

In Slintensity, we have:

Banaba blend-standardized Corosolic Acid and Elagitannins (150mg)-

Banaba leaf can help with glucose control. One study showed that it reduced blood glucose levels 20-30% in users. Studies have also shown reduced total cholesterol levels, increased HDL cholesterol levels, and reduced insulin levels. A dose for banaba leaf is 1-2g

Oh-isoleucine- std 40% (75mg).

I believe this comes from fenugreek seed, which can improve insulin sensitivity and blood glucose levels. A dose for fenugreek seed is 2-3g.

Bitter melon extract std for 35% momordin (100mg)

Bitter Melon can reduce blood glucose levels and total cholesterol levels. A dose for bitter melon is 300mg.

FMOC-L-Leucine (100mg)- I couldn't figure out what this is.

Phellodendrill Cortex 20: 1- Std berberine and obacucone (175mg)-

Berberine can reduce blood glucose levels, reduce total cholesterol, particularly LDL cholesterol. A dose for berberine is 1-2g.

Green Curry Leaf Extract 10:1 (150mg)- I couldn't find much information on this ingredient.

--Dosing----

No taste or mixability here. Slintensity is a pill product.

The dose is 1 pill per 60g carbohydrates. I only used 1 pill at a time, and I used it at dinner, as my dinners are often 50-70g carbs. Also, insulin sensitivity tends to go down during the day, so it made more sense to me to use GDAs at dinner than at breakfast.

The pills are fairly small (about the length of a fingertip) and were easy to swallow.

Effectiveness

I didn't get any blood work done, so I can't say if this product had any impact on my blood glucose levels, cholesterol levels, etc. My numbers were all good at my last doctor's appointment, so any differences would have been minor.

However, I do think this product was effective for me.
With Slintensity, I had no bloating after eating a high carb meal, which is sometimes a problem for me. I was also noticeably leaner over the past month.
The scale only went down 3-4lbs, but my stomach is noticeably smaller as are my thighs. Those are both problem areas for me.

I also had improved definition in my calves, which didn't have a lot of fat before, but any positive results, I will take.

Value

I think the value is pretty fair. I've seen Slintensity go for $26-29 a bottle, and depending on your macros, one bottle could last about two months (assuming a high carb meal every day). If you don't use it every day, one bottle could last longer.

This seems in line with other GDAs on the market, which I've seen range from $20-$50 for 60 servings.

Side Effects

I had no side effects.

This is worth noting because several of the common ingredients in GDAs are known to cause gastrointestinal distress (e.g. berberine). I think my lack of issues was because Slintensity uses standardized extracts instead of raw powders. This way, not as much of the ingredients are needed and the potential for stomach issues is reduced.

Conclusion

For those who want a GDA, I think Slintensity is wort considering. It's effective. It's pretty fairly priced, and I had no side effects.



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